Variation of eye pigmentation (melanin)

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Below:  Pictures of retinas of HPS patients showing:



       Series of three pictures showing the variation of pigmentation in the fundi (retinas) of HPS patients.  This picture shows a very pale or blonde fundus from a HPS-1 patient.      Series of three pictures showing the variation of pigmentation in the fundi (retinas) of HPS patients.  This picture shows a or blonde fundus.from a HPS-1 patient.      Series of three pictures showing the variation of pigmentation in the fundi (retinas) of HPS patients.  This picture shows moderate hypopigmentation of the fundus from a HPS-3 patient..


From left to right: HPS-1, HPS-1, HPS-3.

Below: Pictures of the front of the eyes of HPS patients showing:



                One of a series of three pictures showing the varying pigmentation seen in the Irises (irids) of patients with HPS on trans-illumination of the eye.  In this picture from a HPS-1 patient the Iris and pupil are almost completely transparent with a red reflex showing.  A characteristic cartwheel pattern of eumelanin pigmentation the iris can be seen.       One of a series of three pictures showing the varying pigmentation seen in the Irises (irids) of patients with HPS on trans-illumination of the eye. In this picture from a HPS-3 patient there is markedly more melanin pigment present in the iris and the red reflex is much reduced in comparison to the previours pictures taken from HPS-1 patients.


From left to right: HPS-1, HPS-1. HPS-3.

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